Basic Information
VIS ID
TVIS30016255
Fusion event
HIV-chr4 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.23
Reference genome
GRCh37/hg19
Start
148642310/147721159 (Hg38)
End
148642069/147721159 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/376442; hsa-mir-1305/Downstream/61436;
Nearest TSS
ENST00000502981/Upstream/36929; ENST00000510379/Downstream/10904;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/36685, chr4-CpG: 118/Downstream/10538
Nearby gene
ARHGAP10(No orient, 11142)
Upstream sequence
gattagtcatgtcacagaagaaaccccatggtggatgataaacgttaaaactctttacaggttgggtgcggtggctcatgcctgtaatcccagcactttg
Downstream sequence
ggaggctgaggcgggcagatcacaaggtcaggagatcgagaccatcctggctaacacggtgaaaccccacctctactaaaaaaatacaaaaaaattagct
Target sequence
ttcacagagtggtatgtaaacatcctgttgtagctaaacatgttaaattgccatctttgggcctagctttcttaataacttctactttttgaagtagatgcagatgttttccagcagccttggaccctctggttttcatgtgattagtcatgtcacagaagaaaccccatggtggatgataaacgttaaaactctttacaggttgggtgcggtggctcatgcctgtaatcccagcactttg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate