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TVIS30016259
Basic Information
VIS ID
TVIS30016259
Fusion event
HIV-FBXW7 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
153449909/152528757 (Hg38)
End
153449882/152528757 (Hg38)
Orient
-
Location type
Intronic
Target gene
FBXW7
miRNAs that regulate target gene
hsa-mir-197-3p
;
hsa-mir-107
;
hsa-mir-128-3p
;
hsa-mir-223-3p
;
hsa-mir-27a-3p
;
hsa-mir-590-3p
;
hsa-mir-103a-3p
;
hsa-mir-101-3p
;
hsa-mir-16-5p
;
hsa-mir-503-5p
;
hsa-mir-182-5p
;
hsa-mir-25-3p
;
hsa-mir-510-3p
;
hsa-mir-4639-5p
;
hsa-mir-2052
;
hsa-mir-4328
;
hsa-mir-4698
;
hsa-mir-570-5p
;
hsa-mir-548ba
;
hsa-mir-548ai
;
hsa-mir-548ag
;
hsa-mir-203a-3p
;
hsa-mir-1303
;
hsa-mir-664b-3p
;
hsa-mir-190a-3p
;
hsa-mir-579-3p
;
hsa-mir-380-3p
;
hsa-mir-411-3p
;
hsa-mir-379-3p
;
hsa-mir-4495
;
hsa-mir-656-3p
;
hsa-mir-5011-5p
;
hsa-mir-5694
;
hsa-mir-32-5p
;
hsa-mir-92a-3p
;
hsa-mir-384
;
hsa-mir-363-3p
;
hsa-mir-182-3p
;
hsa-mir-155-3p
;
hsa-mir-770-5p
;
hsa-mir-155-5p
;
hsa-mir-24-3p
;
hsa-mir-223-5p
;
hsa-mir-367-3p
;
hsa-mir-1302
;
hsa-mir-144-3p
;
hsa-mir-296-3p
;
hsa-mir-3122
;
hsa-mir-3192-5p
;
hsa-mir-3529-3p
;
hsa-mir-3913-5p
;
hsa-mir-4252
;
hsa-mir-4298
;
hsa-mir-4425
;
hsa-mir-4701-5p
;
hsa-mir-588
;
hsa-mir-6823-5p
;
hsa-mir-92a-1-5p
Nearest miRNA
hsa-mir-12113/Upstream/39341; hsa-mir-1305/Downstream/7671;
Nearest TSS
ENST00000502981/Upstream/116151;
ENST00000515789/Downstream/6434;
Nearest CpG islands
None/Target,
chr4-CpG: 46/Upstream/767618
,
chr4-CpG: 144/Downstream/6199
Nearest cancer related gene
FBXW7
(TSG, No orient, 0)
Upstream sequence
AATTACTAGAAGATATATATCCCATAGTGTTCAGAAAATGTCACGTACTTTGAGAAAATACATTCCATTTAAACATACTGTGAAAGGTATCATGAGGAAG
Downstream sequence
TACCAAGGAGGTATCATCAGAAAGCAGCAAAAACATAAAAGTACATTAAGACATAAAACAGGATATTAAGTGATATTAAAAATATTTTGTAAGGTCTTTT
Target sequence
CATACTGTGAAAGGTATCATGAGGAAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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