Basic Information
VIS ID
TVIS30016259
Fusion event
HIV-FBXW7 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.3
Reference genome
End
153449882/152528757 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-12113/Upstream/39341; hsa-mir-1305/Downstream/7671;
Nearest cancer related gene
FBXW7(TSG, No orient, 0)
Upstream sequence
AATTACTAGAAGATATATATCCCATAGTGTTCAGAAAATGTCACGTACTTTGAGAAAATACATTCCATTTAAACATACTGTGAAAGGTATCATGAGGAAG
Downstream sequence
TACCAAGGAGGTATCATCAGAAAGCAGCAAAAACATAAAAGTACATTAAGACATAAAACAGGATATTAAGTGATATTAAAAATATTTTGTAAGGTCTTTT
Target sequence
CATACTGTGAAAGGTATCATGAGGAAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate