Basic Information
VIS ID
TVIS30016274
Fusion event
HIV-chr5 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
40254713/40254611 (Hg38)
End
40254964/40254611 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA5A
Nearest miRNA
hsa-mir-10397/Upstream/1697050; hsa-mir-103a-1/Downstream/13696893;
Nearest TSS
ENST00000502646/Upstream/14438; ENST00000508437/Downstream/6046;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/532878, chr5-CpG: 191/Downstream/424789
Nearby gene
PTGER4(No orient, 425318)
Upstream sequence
TATGGCTTTTCAAATTGAGGTCAGGAATGTTCAGCATGTAATCCTAACCATGCAGGTAAATTTGTAAAGTAGGCTGTTGAGTGCCAGCTTTCAAATATCA
Downstream sequence
AGATAGACAGTAAGGTTTAGttgttttgctttattttgttttgttttgttttgGAGGGGATGAGGACTTAGGTAGTTTTGGTTCTCAGTGTCCAAGCAAT
Target sequence
CTAACACCACCtgttaagacatttagtttattgcttaatataacaccatctatctccacaaagtttcagcagtgtcatgaagggaatagggcaagaacagaatttattaagaattggaaattttgtgtaagatggggaaaagtgaaagggaggacttgattaggattgtataagaattaacaacttttctggactgctggaaatagcaaggtaaagatgttggcacaaaagattcaaagatcttTCCAGTA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate