Basic Information
VIS ID
TVIS30016282
Fusion event
HIV-chr5 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
55309350/56013522 (Hg38)
End
55309279/56013522 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA5H
Nearest miRNA
hsa-mir-10397/Upstream/504596; hsa-mir-103a-1/Downstream/2516521;
Nearest TSS
ENST00000502646/Upstream/18355; ENST00000511861/Downstream/45498;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/17961, chr5-CpG: 59/Downstream/467255
Nearby gene
IL6ST(No orient, 18529)
Upstream sequence
gccAGAATTAGAGTTATAATTAAGGCAGGACGTGCCAAGGTGATCACAGCCAAAGGTCCCACTGTGACCTGGGAATGCGGTTGTTGTTAGCAGCGGCAAC
Downstream sequence
AACTGGTACTTCACCCAATCCCTCATTTCCATAGATCAACACAATCtccatctatagcaaacatttacttagcatctgtggagtgccatgctcaacgtca
Target sequence
ACGTGCCAAGGTGATCACAGCCAAAGGTCCCACTGTGACCTGGGAATGCGGTTGTTGTTAGCAGCGGCAAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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