Basic Information
VIS ID
TVIS30016287
Fusion event
HIV-BDP1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
70764843/71469016 (Hg38)
End
70764769/71469016 (Hg38)
Orient
-
Location type
Intronic
Target gene
BDP1
miRNAs that regulate target gene
hsa-mir-30b-5p ; hsa-mir-186-5p ; hsa-mir-3120-5p ; hsa-mir-4495 ; hsa-mir-4698 ; hsa-mir-4743-3p ; hsa-mir-6888-3p ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-944 ; hsa-mir-4511 ; hsa-mir-3133 ; hsa-mir-194-3p ; hsa-mir-5693 ; hsa-mir-6074 ; hsa-mir-4793-5p ; hsa-mir-205-5p ; hsa-mir-5196-3p ; hsa-mir-3614-3p ; hsa-mir-3646 ; hsa-mir-4652-3p ; hsa-mir-8063 ; hsa-mir-4674 ; hsa-mir-7156-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-4437 ; hsa-mir-378g ; hsa-mir-1184 ; hsa-mir-1304-3p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-6890-3p ; hsa-mir-4714-3p ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418 ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6740-3p ; hsa-mir-3182 ; hsa-mir-4778-3p ; hsa-mir-215-3p ; hsa-mir-6773-3p ; hsa-mir-1182 ; hsa-mir-4524b-3p ; hsa-mir-193a-5p ; hsa-mir-4764-3p ; hsa-mir-2681-3p ; hsa-mir-150-5p
Nearest miRNA
hsa-mir-10397/Upstream/11765313; hsa-mir-103a-1/Downstream/700451;
Nearest TSS
ENST00000502646/Upstream/13330; ENST00000508157/Downstream/25449;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/12956, chr5-CpG: 49/Downstream/118093
Upstream sequence
TATTTCTAATGCGAATAATGTTCTACCTCAGATAATATTGTATAATAAAGCTTCTATAGATAAATATGCTGTTAAAAATCTGTTGCATGTTGGTGCTTAT
Downstream sequence
TGTTTTTATTTTAAAAACAGTAGTTTTGAGGAAAAATTCAAACAGCAGGATATAGAGTAAAAAGATTCTATACTTCCCTTCTTTCACTTCCCTATTCCTA
Target sequence
CTCAGATAATATTGTATAATAAAGCTTCTATAGATAAATATGCTGTTAAAAATCTGTTGCATGTTGGTGCTTAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate