Basic Information
VIS ID
TVIS30016292
Fusion event
HIV-ZFYVE16 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
79770868/80475049 (Hg38)
End
79770519/80475049 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZFYVE16
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-615-3p ; hsa-mir-106b-5p ; hsa-mir-222-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-10397/Upstream/7596386; hsa-mir-103a-1/Downstream/2365106;
Nearest TSS
ENST00000502646/Upstream/15610; ENST00000502608/Downstream/12904;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/66424, chr5-CpG: 65/Downstream/12767
Upstream sequence
CTACACACTTCACATATATTATCTGTATTAGTCTCCACAAcaggggtcagcaaactgtttttgcaaaaggacagacagtaactattttggacattgtagg
Downstream sequence
cagtatggtttctttcacaactactcaacactaccattatattgggaaagcagccattcacagtatgtaaacaaattaagtgtggctatgttccagtgaa
Target sequence
ATCAACTTCTTATCAGTTTGCAAAAGAAATAGCCATGGCTTGTAGTGCTGCGCTGTGCCCTCACCTGAAAACTCTAAAAAGTAATGGGATGAATAAAATTGGACTCAGAGTTTCCATTGACACTGATATGGTGAGGCATGTTTTTGTGATGTATTTTTGAAATGAATGTATTGCATATTAACAAGTTTTTCTTCAACCTTTTATTTTGGGATGAAAGGGAACGAAAATTTGTTGAGCATCAAATGTGTGCTACAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate