Basic Information
VIS ID
TVIS30016295
Fusion event
HIV-RASGRF2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
80383783/81087964 (Hg38)
End
80383984/81087964 (Hg38)
Orient
+
Location type
Intronic
Target gene
RASGRF2
Nearest miRNA
hsa-mir-10397/Upstream/8209301; hsa-mir-103a-1/Downstream/1752191;
Nearest TSS
ENST00000502646/Upstream/17940; ENST00000512186/Downstream/4952;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/126777, chr5-CpG: 39/Downstream/213537
Upstream sequence
TACCATAATGTACTGCTTAAAATCTCTTTTTACCTCATCAAGAACAAGACAATGTTTTGTGCACATTAATTTTTGCACAGACTACTTTAAAAGTTTAATG
Downstream sequence
cacattggcttcctgcctgccagcctctgtgcctttccttgtgctgtccccagcctgggggctgggaatgtccttatccatttcttttgtgcctgttgaa
Target sequence
CATGCCATTCTATTTTCCATTATTTATTTACAAGGAGAAACCACACATATGTTAAAGTTTGGGAGTGTATTTTAGGAAATGATTCCTTTTCTCATTTTTGGCTTTAGATATTCTTTTTTCTTTAAATAAGGGTGGAATATAATGCTGACAACATCAGGCCCTTGTAATGcctcctctattcctctgcacagactgtgtccc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate