Basic Information
VIS ID
TVIS30016303
Fusion event
HIV-chr5 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
109702534/110366833 (Hg38)
End
109702783/110366833 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/9550268; hsa-mir-103a-1/Downstream/146996;
Nearest TSS
ENST00000502646/Upstream/483651; ENST00000508781/Downstream/63268;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/481335, chr5-CpG: 60/Downstream/372071
Nearby gene
TMEM232(No orient, 52663)
Upstream sequence
GTTTTAATCTCTAACCTTTCTAATAGAAGAAGACAGACCATTTTGGAAGGATAATGGGTAGTTCTTGGAATAGAAGGAATGACTTGGAAAATGAAAAGCT
Downstream sequence
tgtgtgtgtgtgtgtgtgGtttttgttgttgttgttgtttttgagacaaagtcttgctctgtcacccaggctggagtacagtggtgcaatcttggctcac
Target sequence
GAGGTAAGACAGGCGATGAGGACTACTGCTGAGATCACACCTAGGAGGAATCTGGTTGGAATGCCACCACCTGCACTGTCCCTGTATCTTGGCCCCTGTACCCACATTGGCCCCACTGCTGCAGGACTAGCAGACAGTAAATACCACTGCTGTCCTGACGCCTCCTCATACAGAGCTGCCACTGCTTTCGTGATGCTACTGTTTCTGTCTCTGCTGCTTCTGGACTATTCTTTGTCTTTtgtgtgtgtg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate