Basic Information
VIS ID
TVIS30016304
Fusion event
HIV-YTHDC2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
112876468/113540771 (Hg38)
End
112876075/113540771 (Hg38)
Orient
-
Location type
Intronic
Target gene
YTHDC2
miRNAs that regulate target gene
hsa-mir-505-3p ; hsa-mir-30c-5p ; hsa-mir-96-5p
Nearest miRNA
hsa-mir-10397/Upstream/3026856; hsa-mir-103a-1/Downstream/2714972;
Nearest TSS
ENST00000502646/Upstream/26625; ENST00000506333/Downstream/24948;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/26486, chr5-CpG: 76/Downstream/514603
Upstream sequence
caatcacctcccaccaggtctttccctcaacacctgcgaattataattcaagatgagatgtgggtggagacataaagcctaaccatatcaATGAAGTTTT
Downstream sequence
CAAGCAGTTTCATGTGTCTTTTTGTTTCAGCATAACACatttttattgaatattcttaatatattttttaaaaGTAACTACAGAATAAGACCAACTTTTA
Target sequence
AATAGGTGAATGCATGAAtgtattagcccattttcacactgctgtaaagatactacctgagacttggaaatttataaagaaaagaggtttaattcactcacagttctgcatggctggggaggcctcaggaaacttagtcatgatggaaggcaaaggggaagcaaggaccttctttacatggcagcaagagagagaagtgcaagcaagggaaataccagatgcttataaaaccatcagatctcgtgagaactcact
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate