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TVIS30016326
Basic Information
VIS ID
TVIS30016326
Fusion event
HIV-UBE2D2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
138977164/139597579 (Hg38)
End
138977232/139597579 (Hg38)
Orient
+
Location type
Intronic
Target gene
UBE2D2
miRNAs that regulate target gene
hsa-mir-155-5p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-let-7b-5p
;
hsa-mir-10a-5p
;
hsa-mir-30c-5p
;
hsa-mir-105-5p
;
hsa-mir-130a-3p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-518a-5p
;
hsa-mir-527
;
hsa-mir-559
;
hsa-mir-548b-5p
;
hsa-mir-548a-5p
;
hsa-mir-548c-5p
;
hsa-mir-548d-5p
;
hsa-mir-454-3p
;
hsa-mir-301b-3p
;
hsa-mir-548j-5p
;
hsa-mir-548h-5p
;
hsa-mir-548i
;
hsa-mir-548w
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-3668
;
hsa-mir-548y
;
hsa-mir-548o-5p
;
hsa-mir-548ab
;
hsa-mir-548ad-5p
;
hsa-mir-548ae-5p
;
hsa-mir-548ak
;
hsa-mir-548am-5p
;
hsa-mir-3973
;
hsa-mir-4671-3p
;
hsa-mir-548ap-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548as-5p
;
hsa-mir-548au-5p
;
hsa-mir-548ay-5p
;
hsa-mir-7853-5p
;
hsa-mir-548bb-5p
;
hsa-mir-4274
;
hsa-mir-4694-3p
;
hsa-mir-3924
;
hsa-mir-4473
;
hsa-mir-7852-3p
;
hsa-mir-944
;
hsa-mir-4674
;
hsa-mir-4437
;
hsa-mir-5093
;
hsa-mir-551b-5p
;
hsa-mir-376b-3p
;
hsa-mir-376a-3p
Nearest miRNA
hsa-mir-10397/Upstream/1949930; hsa-mir-103a-1/Downstream/966092;
Nearest TSS
ENST00000502646/Upstream/35550;
ENST00000511691/Downstream/1983;
Nearest CpG islands
None/Target,
chr5-CpG: 87/Upstream/35372
,
chr5-CpG: 52/Downstream/39899
Upstream sequence
ATGGATCTTGTATTCTGCTTAGATAAATCTTAGCTCTTGAGTTAAAAACCTTGATGTTATTCAGCATGGAAAAAAGTAACTCAGTTTGAAAGGGGCAAAA
Downstream sequence
TTAAATTGTTAAATTCAAGTTATATTTTAATTAACAACCTGTTGCTATAGCAATGTCTTAAATAAAGCCAGGTGTTCTTAGTTATACCAACCTGTGCTGT
Target sequence
GATTAAAGCGAAATCAAAAGTAAAATTCCACTTAATGAACATGGCAGGACTTCAGAATTGTTCAATTG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT4
Sample type
PBMC
Age
39
Gender
Male
CpG Island Information
×
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