Basic Information
VIS ID
TVIS30016331
Fusion event
HIV-ANKHD1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
139853110/140473525 (Hg38)
End
139853378/140473525 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANKHD1
miRNAs that regulate target gene
hsa-mir-424-5p ; hsa-mir-320a ; hsa-mir-185-5p
Nearest miRNA
hsa-mir-10397/Upstream/2825876; hsa-mir-103a-1/Downstream/90146;
Nearest TSS
ENST00000502646/Upstream/14268; ENST00000465435/Downstream/9055;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/71002, chr5-CpG: 36/Downstream/74047
Upstream sequence
GATTTTTAAAAATTTTTTAAAttttttttttttgagacagggtctcactctgttgctcaggctggaatgcagtggtgtgctcttggctcactgcagcctt
Downstream sequence
ATTGTTTTTCCCTGGATTTGTTAGATGAAATGTAATTGTAAATCTTTCTCTCTAGCTGCAAGTCTCAAAACAGGATTTTTTTAAAAATGAGTTTTGCAGC
Target sequence
cccatcccaggctcaagtgatcttcctgcctcagcctccccagtagctgggactagaggcatgtgccaccatgcccaactaatttttttcatttttatagagatgaggtctcactgtactgtccaggctggATATATTTATTCTACTTTGAAGTAAGTAAGTTTATTTTACAAAATGTGATGTGAACATGTGAGCTTCTACTCAGTTTGTATAATATTATAGGCTCCTATCAAGAATGTAAAGCTGAGTGTTATT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate