Basic Information
VIS ID
TVIS30016332
Fusion event
HIV-chr5 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
141485741/142106176 (Hg38)
End
141485626/142106176 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/1458250; hsa-mir-103a-1/Downstream/1573684;
Nearest TSS
ENST00000502646/Upstream/93135; ENST00000509436/Downstream/2329;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/93047, chr5-CpG: 82/Downstream/2543
Nearby gene
NDFIP1(No orient, 2582)
Upstream sequence
CGGACATGAGTTATGCTTATACTTGTCCATGTTTCTTTTCTCTCTCAGGAGGGATGATTCAGAGTCAGCAATTCACATATGCAGTACTGCACATGGAAAG
Downstream sequence
TATTACTGTTATTCTGTGGGGAAATAAGTTTCTAAGTGCAGCAATCTGAAATTAATAACTTTCTCTGTGGAAACTCTCTTGACAACATCTCGAGATGAAG
Target sequence
AGGGGGAAAGGGATACGGACATGAGTTATGCTTATACTTGTCCATGTTTCTTTTCTCTCTCAGGAGGGATGATTCAGAGTCAGCAATTCACATATGCAGTACTGCACATGGAAAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate