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TVIS30016340
Basic Information
VIS ID
TVIS30016340
Fusion event
HIV-NSD1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.3
Reference genome
GRCh37/hg19
Start
176580379/177153378 (Hg38)
End
176580220/177153378 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA5G
Target gene
NSD1
miRNAs that regulate target gene
hsa-mir-423-5p
;
hsa-mir-615-3p
;
hsa-mir-186-5p
;
hsa-mir-149-5p
;
hsa-mir-23b-3p
;
hsa-mir-374a-5p
;
hsa-mir-1470
;
hsa-mir-3190-3p
;
hsa-mir-1238-5p
;
hsa-mir-3659
;
hsa-mir-4658
;
hsa-mir-4758-5p
;
hsa-mir-6790-5p
;
hsa-mir-3927-3p
;
hsa-mir-6831-5p
;
hsa-mir-6758-5p
;
hsa-mir-6856-5p
;
hsa-mir-218-5p
;
hsa-mir-5581-3p
;
hsa-mir-6832-5p
;
hsa-mir-4451
;
hsa-mir-6077
;
hsa-mir-486-3p
;
hsa-mir-7-5p
;
hsa-mir-2115-5p
;
hsa-mir-298
;
hsa-mir-4745-5p
;
hsa-mir-4481
;
hsa-mir-3184-5p
;
hsa-mir-6743-5p
;
hsa-mir-4688
;
hsa-mir-4500
;
hsa-mir-4458
;
hsa-let-7i-5p
;
hsa-let-7d-5p
;
hsa-let-7b-5p
;
hsa-let-7a-5p
;
hsa-mir-98-5p
;
hsa-let-7g-5p
;
hsa-let-7c-5p
;
hsa-let-7f-5p
;
hsa-let-7e-5p
;
hsa-mir-6749-3p
;
hsa-mir-6792-3p
;
hsa-mir-4691-5p
;
hsa-mir-4469
;
hsa-mir-5695
;
hsa-mir-3667-3p
;
hsa-mir-4667-3p
;
hsa-mir-4286
;
hsa-mir-1224-3p
;
hsa-mir-6809-5p
;
hsa-mir-4708-3p
;
hsa-mir-3922-5p
;
hsa-mir-4717-5p
;
hsa-mir-4753-5p
;
hsa-mir-6513-5p
;
hsa-mir-5089-5p
;
hsa-mir-6728-5p
;
hsa-mir-769-3p
;
hsa-mir-450b-3p
;
hsa-mir-4303
;
hsa-mir-513b-5p
;
hsa-mir-3147
;
hsa-mir-4425
;
hsa-mir-664a-5p
;
hsa-mir-4794
;
hsa-mir-4682
;
hsa-mir-125b-2-3p
;
hsa-mir-4457
;
hsa-mir-6874-3p
;
hsa-mir-148b-5p
;
hsa-mir-3943
;
hsa-mir-892b
;
hsa-mir-513b-3p
;
hsa-mir-27b-3p
;
hsa-mir-27a-3p
Nearest miRNA
hsa-mir-10397/Upstream/523878; hsa-mir-1229/Downstream/2644900;
Nearest TSS
ENST00000502646/Upstream/18211;
ENST00000375350/Downstream/58733;
Nearest CpG islands
None/Target,
chr5-CpG: 87/Upstream/18727
,
chr5-CpG: 24/Downstream/112961
Nearest cancer related gene
NSD1
(OG, No orient, 0)
Upstream sequence
ttgatgtacttatttctggatggctttccaaaaggattttaccattttacacacagttctaaatagtatatgaatttagcatttgtcccacacttagata
Downstream sequence
gcactgatttttttttttattaagtgggtgcaaaatgctactacaagattgctttaattactacagttttattgatGAAAATGATTTCTACTTGTTTACT
Target sequence
tttaattatttcttgaggattaactgctgatagtggaatatcatatatatagttggctcttgatgtacttatttctggatggctttccaaaaggattttaccattttacacacagttctaaatagtatatgaatttagcatttgtcccacacttagata
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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