Basic Information
VIS ID
TVIS30016347
Fusion event
HIV-chr5 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.3
Reference genome
GRCh37/hg19
Start
178246398/178819397 (Hg38)
End
178246419/178819397 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA5G
Nearest miRNA
hsa-mir-10397/Upstream/2189897; hsa-mir-1229/Downstream/978881;
Nearest TSS
ENST00000502646/Upstream/88695; ENST00000520377/Downstream/40556;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/88572, chr5-CpG: 102/Downstream/40476
Nearby gene
ZNF354B(No orient, 40555)
Upstream sequence
agaagcactcagcctctttaggcctcagtgttcttatcttcaaaatgggaattatactgatatctTTCtatggcagagactgctgttctgccctagttgc
Downstream sequence
agaaccccatttttggactaggcatatggctccccaggatggagattgcatatcctagcccctctgttagttagatatggccctgtctgtaccctccaac
Target sequence
cagtctcacttccaaagtgac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate