Basic Information
VIS ID
TVIS30016349
Fusion event
HIV-chr5 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.3
Reference genome
GRCh37/hg19
Start
180401794/180974794 (Hg38)
End
180401679/180974794 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/959397; hsa-mir-4638/Downstream/68609;
Nearest TSS
ENST00000502646/Upstream/63305; ENST00000342868/Downstream/14051;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/4231, chr5-CpG: 131/Downstream/77791
Nearby gene
BTNL3(No orient, 14050)
Upstream sequence
aggaactaacactcaactcaatagcaatgaaacaaataatccagtttttaaaacgggcaaaggtcctgaatagacacatctaaaaagaagacatacaaat
Downstream sequence
gactaacaggaatataaaaatgtccaacatcattaatcatcagggaaatgacaatcgaaaccatgagataccatctcacaactgttaggatagccattat
Target sequence
tactcaagatacataaggaactaacactcaactcaatagcaatgaaacaaataatccagtttttaaaacgggcaaaggtcctgaatagacacatctaaaaagaagacatacaaat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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