Basic Information
VIS ID
TVIS30016351
Fusion event
HIV-chr5 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q35.3
Reference genome
GRCh37/hg19
Start
180682940/181255939 (Hg38)
End
180683016/181255939 (Hg38)
Orient
+
Location type
Intronic
Target gene
CTC-338M12.4 ; TRIM52
Nearest miRNA
hsa-mir-10397/Upstream/33306;
Nearest TSS
ENST00000502646/Upstream/7843; ENST00000412295/Downstream/4255;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/8789, chr5-CpG: 84/Downstream/5111
Nearby gene
TRIM52(No orient, 445)
Upstream sequence
AAGTATAGATTATTTTTCATTGTTCTTCCAACCTTGGGGTTGTTCTGTCCACAAGTTCAGCAGAATCCGTTTTTCTTTGGCAACCAAGAAACTTCAATAT
Downstream sequence
GTGGTCTATGCTGACAGCAAGGCTGAAGATTTCCAGTAGGTTATGGGTAATCAGTGAAAGTTCATGCTTGGTGGTGACAGCTGCAGTACATCTTGAATAC
Target sequence
GTAACAGAAAACATGGAATGGCATTTAGATCTTCAAAAAGCAGGGCAAACTGGAATGGAATGTACTGTTTCTCACA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate