Basic Information
VIS ID
TVIS30016353
Fusion event
HIV-FARS2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
5549091/5548858 (Hg38)
End
5549033/5548858 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6B
Target gene
FARS2
Nearest miRNA
hsa-mir-3691/Upstream/400536; hsa-mir-10398/Downstream/620446;
Nearest TSS
ENST00000381078/Upstream/90783; ENST00000454882/Downstream/146414;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/287156, chr6-CpG: 29/Downstream/302519
Upstream sequence
AATGTCATTTTTTTTCTCCTTTCTGCCTTCAAATTTGAAAGCCAATATATGCATACCTGCACTAATATATAATTTTTATAGTTGTCTTTGTGTAACAAAC
Downstream sequence
TTAAGAACTTCTAACGGGGCAATTAGGATTTGTACATTCATATTTAGTATATGTTCATAAAATACTTTGTGAAGTATAGATTATAGATCATACTATTACC
Target sequence
CAATATATGCATACCTGCACTAATATATAATTTTTATAGTTGTCTTTGTGTAACAAAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate