Basic Information
VIS ID
TVIS30016355
Fusion event
HIV-ADTRP integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p24.1
Reference genome
GRCh37/hg19
Start
11716795/11716562 (Hg38)
End
11716864/11716562 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADTRP
Nearest miRNA
hsa-mir-3691/Upstream/1276768; hsa-mir-10398/Downstream/4424994;
Nearest TSS
ENST00000381078/Upstream/109010; ENST00000412132/Downstream/11995;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/177866, chr6-CpG: 37/Downstream/292538
Upstream sequence
GAAATGCCCACATACCCATCCACATGCTAGAGAAGGCACTGTTCCCAAATGGGTCTCTGTGGTGCTCCCAAAGTCATTTTATTCTGTAGGGACTCATGTG
Downstream sequence
TTGAATTCTCACAGAGCTAAGCAGTTTGTAGGCTTCTTTAAGTCTTCAAAATTTATCTCTGACCATGCtttttttctttttctttttctttttttttttt
Target sequence
GCGTGAACGTTGCAAAAATCATGTTTCTTTTTGCTTCTAGCAGCTGGGAATGGCAAGCGGGTCTTAGTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate