Basic Information
VIS ID
TVIS30016359
Fusion event
HIV-LOC101928354 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p23
Reference genome
GRCh37/hg19
Start
14693616/14693385 (Hg38)
End
14693682/14693385 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6A
Target gene
LOC101928354
Nearest miRNA
hsa-mir-3691/Upstream/4253591; hsa-mir-10398/Downstream/1448171;
Nearest TSS
ENST00000381078/Upstream/93695; ENST00000474854/Downstream/328579;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/481872, chr6-CpG: 113/Downstream/551261
Nearby gene
JARID2(No orient, 552910)
Upstream sequence
agacaggatctgaatttaagtttacccttTCTTAAGAAGTCATTTCTTTCTGACAGTGTAAAGAAATATTTTAAATAAGATTTTAGAGCCAAATATTTAA
Downstream sequence
tagcatgaacttgaaagttatctgattatctattacacaattctataattcagactgtttcTTGAATTAGAAAGTCTACTGAGATGTTAGGGTAAACTCC
Target sequence
GAGATCAAACTCAATATTGTAAAAATTTACAAAAGAAAAAGACACGATttagcccaatttaattta
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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