Basic Information
VIS ID
TVIS30016360
Fusion event
HIV-DTNBP1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
15603556/15603325 (Hg38)
End
15603584/15603325 (Hg38)
Orient
+
Location type
Intronic
Target gene
DTNBP1
Nearest miRNA
hsa-mir-3691/Upstream/5163531; hsa-mir-10398/Downstream/538231;
Nearest TSS
ENST00000381078/Upstream/17310; ENST00000451285/Downstream/59595;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/85999, chr6-CpG: 95/Downstream/58888
Upstream sequence
TCAGTCTGTTTTCAAGAGGTCATTGGCCTAGTAAATGTGATTACattataataaatacaataaaataaaaatGTCAATTTACTTTCAATTAACCACCTGG
Downstream sequence
GGAGAGGGGGGAGTAAAAGGAGAAAATGGAGAAAAGAGATACAAGtttcagccttttttatattttccatgtctctacttcactttttgaacagaataca
Target sequence
GAACCATCTAAAATCTAGCATCTAATAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate