Basic Information
VIS ID
TVIS30016361
Fusion event
HIV-NUP153 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
17654159/17653928 (Hg38)
End
17654181/17653928 (Hg38)
Orient
+
Location type
Intronic
Target gene
NUP153
miRNAs that regulate target gene
hsa-mir-374b-5p ; hsa-mir-26b-5p ; hsa-mir-744-5p ; hsa-mir-106b-3p ; hsa-mir-330-3p ; hsa-mir-93-5p ; hsa-mir-23a-3p ; hsa-let-7b-5p ; hsa-mir-4696 ; hsa-mir-125a-3p ; hsa-mir-6888-5p ; hsa-mir-4524b-3p ; hsa-mir-552-3p ; hsa-mir-5680
Nearest miRNA
hsa-mir-3691/Upstream/1512304; hsa-mir-10398/Downstream/917856;
Nearest TSS
ENST00000381078/Upstream/53573; ENST00000606771/Downstream/52329;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/52762, chr6-CpG: 117/Downstream/52133
Upstream sequence
gcatttgtcaaatttattaaatggcacacctaagaatttaacatttcactatatgtcaattttgctatgttataaaaagaacaacaaatatttaactcta
Downstream sequence
tatttgggggtgaagtgtactaatgtcttcaactatctttaaaatgcaccaaaaaataaaaaaagatggacaggtaaatttttcttttttgataaagcaa
Target sequence
cttcacgctatgtatgctgacg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate