Basic Information
VIS ID
TVIS30016362
Fusion event
HIV-chr6 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
17713350/17713119 (Hg38)
End
17713226/17713119 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-3691/Upstream/1571495; hsa-mir-10398/Downstream/858665;
Nearest TSS
ENST00000381078/Upstream/6285; ENST00000546309/Downstream/81578;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/6011, chr6-CpG: 123/Downstream/274102
Nearby gene
NUP153(No orient, 6532)
Upstream sequence
AACTTCTGTTCCTTACTAATCTACAACAATCAACAATTTAAGAATTGATGAACCAACAGCTTATACAACATGTAGTTTTTTTTCCTCTTCTTTATCATTC
Downstream sequence
TGTACCTTTCTCCTTTACCACAAAGTGAGCAGAAATGGAATGAACCATTTTTTAATTATTCTTTCATTAACTTTTTTTTTCCAAAGGAAAAAGGTAATCT
Target sequence
GTTCCCGTAAAGAGCAGGCTTAGGAACTTCTGTTCCTTACTAATCTACAACAATCAACAATTTAAGAATTGATGAACCAACAGCTTATACAACATGTAGTTTTTTTTCCTCTTCTTTATCATTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate