Basic Information
VIS ID
TVIS30016366
Fusion event
HIV-RIPOR2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
24861526/24861298 (Hg38)
End
24861453/24861298 (Hg38)
Orient
-
Location type
Intronic
Target gene
RIPOR2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-374a-5p ; hsa-mir-4674 ; hsa-mir-4314 ; hsa-mir-6749-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-4437 ; hsa-mir-6778-3p ; hsa-mir-378g ; hsa-mir-4486 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-532-3p ; hsa-mir-1224-3p ; hsa-mir-6877-3p ; hsa-mir-6819-3p
Nearest miRNA
hsa-mir-3691/Upstream/6289418; hsa-mir-10398/Downstream/2286328;
Nearest TSS
ENST00000381078/Upstream/18162; ENST00000428903/Downstream/16057;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/85797, chr6-CpG: 82/Downstream/49100
Upstream sequence
GATCTGAGtctaagcccaccttttagtgtacaggaaatttagggcatagatgagcaagtcagattatatcaaaaatagacacattcagaatgtggggtag
Downstream sequence
tctataggaattagcatgaattctacaaaaaggcagtatcataggggaaaaaatttctacataaagagactagacaaacataatcaccaaatgtaacaac
Target sequence
gtacaggaaatttagggcatagatgagcaagtcagattatatcaaaaatagacacattcagaatgtggggtag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate