Basic Information
VIS ID
TVIS30016370
Fusion event
HIV-chr6 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
26126598/26126370 (Hg38)
End
26126840/26126370 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA6C
Nearest miRNA
hsa-mir-3691/Upstream/7554490; hsa-mir-10398/Downstream/1021256;
Nearest TSS
ENST00000381078/Upstream/2167; ENST00000304218/Downstream/29984;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/1816, chr6-CpG: 56/Downstream/29851
Nearby gene
HIST1H2AC(No orient, 1680)
Upstream sequence
ACTTCCCAGATACTGACACCGGCTCAGGGCGGATCCAGCCTTTTCCGCTCTTCCCTCCCTCCACCCCCTCCTTTCCCTACAACTACTCTCAAAGGAAAAG
Downstream sequence
CTTATGGGCCTTGGAATCCTTTTTATTCACTGACCAAATTGCCTTTGATTCCAGCTCCCAATCGGTGTGTGACCTTGGCCTAGGGCTTAATCTCTTCCTA
Target sequence
GGTTGGATGTCCCATTTGGGTGAAAACAAAGTGGCATAAAAGCAAATGATCACCTTTGATAGCCACATATTAGAATTTTCCGAGGGTATTTTTAAATTACAACGATTCTAATGGGCAGCTGGGCTGAGAATCATCAGATTTGAAGGTCTGGTTTCACATGGCTCTTGGGCTGAGAAGACCGGATTTTCCCCCCCCAGCATTTCCTGTATGTCCGAGAATTTCGATCCTAAGGTTAGAATTGC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate