Basic Information
VIS ID
TVIS30016374
Fusion event
HIV-BTN3A3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
26446751/26446523 (Hg38)
End
26446673/26446523 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6C
Target gene
BTN3A3
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-106b-5p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-21-5p ; hsa-mir-20a-5p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-4660 ; hsa-mir-302a-5p ; hsa-mir-6736-3p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-4274 ; hsa-mir-3163 ; hsa-mir-646 ; hsa-mir-1277-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-548e-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-16-5p ; hsa-mir-503-5p ; hsa-mir-568 ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-223-5p ; hsa-mir-219b-3p ; hsa-mir-22-3p ; hsa-mir-548p ; hsa-mir-186-5p ; hsa-mir-219a-2-3p ; hsa-mir-93-5p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-3691/Upstream/7874643; hsa-mir-10398/Downstream/701103;
Nearest TSS
ENST00000381078/Upstream/985; ENST00000477388/Downstream/2714;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/160811, chr6-CpG: 18/Downstream/11559
Upstream sequence
caaaagagtgctcattctcactcattagggaaacatatctgaaatcatttttcacttatgatattagcaaaaatcaaaaccccactgccttgcttgatac
Downstream sequence
cacatggctatggcaggagtgtaggaaggcagtgactctcagtcatttgctcgtgtcacttgtatttttggtgtgcattagcacaagctctattggggga
Target sequence
cattagggaaacatatctgaaatcatttttcacttatgatattagcaaaaatcaaaaccccactgccttgcttgatac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate