Basic Information
VIS ID
TVIS30016378
Fusion event
HIV-HLA-T integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
29866707/29898930 (Hg38)
End
29866830/29898930 (Hg38)
Orient
+
Location type
Intronic
Target gene
HLA-T
Nearest miRNA
hsa-mir-3143/Upstream/2751242; hsa-mir-10398/Downstream/685402;
Nearest TSS
ENST00000381078/Upstream/25147; ENST00000638375/Downstream/42330;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/10142, chr6-CpG: 86/Downstream/27433
Nearby gene
HLA-H(No orient, 7851)
Upstream sequence
acaagaaatgtctcttccactgttgtattaatattttagatgtaaataacattttttaaaaaaaattttacaggctcaaagctataagaatttatcttga
Downstream sequence
gGGGAtgcaatgatataaacatttatcccctgatacctcatgttaaaatctgatgcccactgtgggacgtggggcctaatggccaccatttgggtcatgg
Target sequence
gtctcagatgagactctggaattttgagttgatgctggaacaacctaacacatttgggacaattgggagaagattattatattttgcaatgtgagaagaacatgacctttggctggctaggga
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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