Basic Information
VIS ID
TVIS30016380
Fusion event
HIV-ZNRD1ASP integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
29990060/30022283 (Hg38)
End
29989875/30022283 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZNRD1ASP
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-3143/Upstream/2874595; hsa-mir-10398/Downstream/562049;
Nearest TSS
ENST00000381078/Upstream/44816; ENST00000471008/Downstream/36616;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/14691, chr6-CpG: 27/Downstream/38876
Upstream sequence
aggaacagcattaactccctcttctggaagtgtgaattcttgatatcatgtaatgaaaatggtacctcacttgtggctttcctccccccgaatccataac
Downstream sequence
ctctacttattatgaaaaaaaaaaaaaaacaaaaaaaaaacaccgaattccaatagaggaacattctataaaatacctaactagtattcctcaataacgt
Target sequence
tgataaataaatcaatggaggagaggaggcaaaatctctcctgcagaagaactccaaataaggtaggtagatactttgtccttaaaggaacagcattaactccctcttctggaagtgtgaattcttgatatcatgtaatgaaaatggtacctcacttgtggctttcctccccccgaatccataac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate