Basic Information
VIS ID
TVIS30016381
Fusion event
HIV-chr6 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.33
Reference genome
GRCh37/hg19
Start
30471478/30503701 (Hg38)
End
30471430/30503701 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-3143/Upstream/3356013; hsa-mir-10398/Downstream/80631;
Nearest TSS
ENST00000381078/Upstream/14189; ENST00000415195/Downstream/12565;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/13303, chr6-CpG: 20/Downstream/51808
Nearby gene
HLA-E(No orient, 9496)
Upstream sequence
TCAAAACCACTTTTCTTGAGCACTGATGAGTAAGTAAGCTTGATACATCATTTCAGTTCCTCAGATGAGCAAAAATCATTAGTTTTATATCATCAGTTTT
Downstream sequence
ATAAGTCTGAAATTTAGTATTTAAGTCACTAATAAAAACACATTTTTGTggccgggcgtggtggctcacacctgtaatcccagcactttgagaggccaag
Target sequence
TCAGTTCCTCAGATGAGCAAAAATCATTAGTTTTATATCATCAGTTTT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate