Basic Information
VIS ID
TVIS30016393
Fusion event
HIV-chr6 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.33
Reference genome
GRCh37/hg19
Start
31537625/31569848 (Hg38)
End
31537551/31569848 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
LOC100287329 ; LTA
miRNAs that regulate target gene
hsa-mir-34a-5p
Nearest miRNA
hsa-mir-3143/Upstream/214532; hsa-mir-10398/Downstream/63939;
Nearest TSS
ENST00000381078/Upstream/21421; ENST00000454783/Downstream/2206;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/27729, chr6-CpG: 80/Downstream/10811
Nearby gene
LTA(No orient, 2250)
Upstream sequence
atcgtgccactgcactccagcctgtgcgacagtgagaaactgtctcaaaaaaaaaaaaaaaggaaaagaaattttctgacctatctcatctgatagtagg
Downstream sequence
ttataagaccctcattccagaagaggttctgccctatacctgggaggaaggaatgctgtacagagagaccaagaagaatatggccaggccttgctgggat
Target sequence
cgacagtgagaaactgtctcaaaaaaaaaaaaaaaggaaaagaaattttctgacctatctcatctgatagtagg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate