Basic Information
VIS ID
TVIS30016395
Fusion event
HIV-chr6 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.32
Reference genome
GRCh37/hg19
Start
32828370/32860593 (Hg38)
End
32828492/32860593 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-1236/Upstream/110614; hsa-mir-10398/Downstream/347242;
Nearest TSS
ENST00000381078/Upstream/4496; ENST00000584808/Downstream/76293;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/6000, chr6-CpG: 35/Downstream/19128
Nearby gene
PSMB9(No orient, 742)
Upstream sequence
atagaggtttggaaagattaaatcacttgaccaaggtcacaaaataagttctgaggctgggatctgggattcagtcttattatatgcccttcctctacca
Downstream sequence
CAAATTTAATTCTGCTTCTATCTTTGCCTTGCACTTCCTGAGTGACAGGAGTGAACTctcatatccttttctgtcaaaagatggtgctgaatgatttcta
Target sequence
ctcCCTAAAACTTCTCATTCCCTCAATCCCCATATATCATCTTAAAATCTGCAATAAATAGCCCCATACATTCGTTGGCACTTAGGAAACTGTTACCAGATGGCTGAGTAACTGTATTAAAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate