Basic Information
VIS ID
TVIS30016399
Fusion event
HIV-chr6 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.32
Reference genome
GRCh37/hg19
Start
32950881/32983104 (Hg38)
End
32950684/32983104 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA6H
Nearest miRNA
hsa-mir-1236/Upstream/233125; hsa-mir-10398/Downstream/224731;
Nearest TSS
ENST00000381078/Upstream/3422; ENST00000469120/Downstream/24280;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/9927, chr6-CpG: 19/Downstream/24803
Nearby gene
BRD2(No orient, 1599)
Upstream sequence
ACTAGTCTCTTAATTGACTTTAGTTTGAACTTATTTCAAGCCTGTCTCACTTAGGGATTGTAATTGTTTCAGGAGTTTGGTTGAGTTCCATCTTGGTTGC
Downstream sequence
CAAAGGACTTTATTCCAAAATAGCAGTCTCCAGCACAACTCAAAGGACTAGTGGAGTCCTGTGGGCATTATTTCCCCCTATGCTCCTCTCAGCTCTTGGA
Target sequence
TAATTCCCTGTAAATGGAACCCAGACCGCCCTAAATGCTTTAAGAGAGAGAAGGGCTGGCTGACACAGGGGCTTCAGACCTGCCTTAAACCAATTGGACTAGTCTCTTAATTGACTTTAGTTTGAACTTATTTCAAGCCTGTCTCACTTAGGGATTGTAATTGTTTCAGGAGTTTGGTTGAGTTCCATCTTGGTTGC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate