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TVIS30016400
Basic Information
VIS ID
TVIS30016400
Fusion event
HIV-VPS52 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.32
Reference genome
GRCh37/hg19
Start
33226084/33258307 (Hg38)
End
33226334/33258307 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
VPS52
miRNAs that regulate target gene
hsa-mir-4728-5p
;
hsa-mir-607
;
hsa-mir-3591-5p
;
hsa-mir-628-5p
;
hsa-mir-3671
;
hsa-mir-6807-5p
;
hsa-mir-124-5p
;
hsa-mir-3175
;
hsa-mir-6731-5p
;
hsa-mir-8085
;
hsa-mir-8077
;
hsa-mir-7160-5p
;
hsa-mir-655-5p
;
hsa-mir-4663
;
hsa-mir-665
;
hsa-mir-4459
;
hsa-mir-4779
;
hsa-mir-4255
;
hsa-mir-7161-3p
;
hsa-mir-302f
;
hsa-mir-142-3p
;
hsa-mir-513b-5p
;
hsa-mir-6829-3p
;
hsa-mir-6791-3p
;
hsa-mir-4252
;
hsa-mir-205-5p
;
hsa-mir-4719
;
hsa-mir-7853-5p
;
hsa-mir-105-5p
;
hsa-mir-330-3p
;
hsa-mir-7109-3p
;
hsa-mir-6771-3p
;
hsa-mir-3065-3p
;
hsa-mir-338-3p
;
hsa-mir-3617-3p
;
hsa-mir-383-3p
;
hsa-mir-500b-3p
;
hsa-mir-6884-3p
;
hsa-mir-7156-3p
Nearest miRNA
hsa-mir-1236/Upstream/50363; hsa-mir-10398/Downstream/28920;
Nearest TSS
ENST00000381078/Upstream/8028;
ENST00000474626/Downstream/5306;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/8621
,
chr6-CpG: 53/Downstream/13242
Upstream sequence
caaaacccatctctactaaatatacaaaaattagccgggcgtggtagcacacgcctgtaatcccagctactcaggaggctgagaaaggataagtgcttga
Downstream sequence
cttataaataaaaaatactagcagacttatttttttctttattttttgagagagtcacgctctgtaactgaggctggagtgcagtggcataatcttggct
Target sequence
acccgggaggcagaggtgcagtgagctgagatcacaccattgcactccagcctcggcaacatgagtgaaactccatctcaaaaaaaaaaaaaaaaaggtgcaaggatttcttgagcccaggagcctgggcaacacagaaagaccctcatctcaccaaaaaaaaaaaaaaaaGTAAAaagatacatactaaaagataatctgtaacctacgtataatcaacaagattagtatgtagatgatgcaaagaact
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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