Basic Information
VIS ID
TVIS30016402
Fusion event
HIV-TAPBP integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.32
Reference genome
GRCh37/hg19
Start
33278341/33310564 (Hg38)
End
33278299/33310564 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
TAPBP
miRNAs that regulate target gene
hsa-mir-7-5p ; hsa-mir-30a-5p ; hsa-mir-744-5p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-100-5p ; hsa-mir-1248 ; hsa-mir-338-3p ; hsa-mir-4530 ; hsa-mir-5690 ; hsa-mir-5586-5p ; hsa-mir-646 ; hsa-mir-4668-5p ; hsa-mir-129-5p ; hsa-mir-3152-5p ; hsa-mir-4774-3p ; hsa-mir-1298-5p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-4778-3p ; hsa-mir-561-3p ; hsa-mir-4327 ; hsa-mir-6499-3p ; hsa-mir-4537 ; hsa-mir-1292-3p ; hsa-mir-4740-3p ; hsa-mir-1246 ; hsa-mir-1290 ; hsa-mir-1291 ; hsa-mir-31-5p ; hsa-mir-3167 ; hsa-mir-328-3p ; hsa-mir-4685-5p ; hsa-mir-515-5p ; hsa-mir-519d-5p ; hsa-mir-519e-5p ; hsa-mir-597-3p ; hsa-mir-6775-3p ; hsa-mir-6837-5p ; hsa-mir-6851-3p ; hsa-mir-876-5p
Nearest miRNA
hsa-mir-1236/Upstream/20239; hsa-mir-10398/Downstream/127767;
Nearest TSS
ENST00000381078/Upstream/11240; ENST00000450504/Downstream/3391;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/10759, chr6-CpG: 58/Downstream/2771
Upstream sequence
cattgcactccagcctgggcaacagggtgagactctgtctcaaaaaaaaaaaaaaaaaaaaaaaaGTATATTTGgggccaggcagctcacacgtgtaatc
Downstream sequence
ccagcagtttcggaggccaaggtgggcagatcaattgagcccaggagtccaagaccagcctgggcaacctgacaaaaacccatctccacaaaaaaaatac
Target sequence
aaaaaaaGTATATTTGgggccaggcagctcacacgtgtaatc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate