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Viral Integration Site DataBase
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TVIS30016405
Basic Information
VIS ID
TVIS30016405
Fusion event
HIV-ILRUN integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
34653953/34686176 (Hg38)
End
34653922/34686176 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
ILRUN
miRNAs that regulate target gene
hsa-mir-484
;
hsa-mir-423-3p
;
hsa-mir-10b-5p
;
hsa-mir-6510-5p
;
hsa-mir-5739
;
hsa-mir-3175
;
hsa-mir-6734-5p
;
hsa-mir-8085
;
hsa-mir-6731-5p
;
hsa-mir-4644
;
hsa-mir-4306
;
hsa-mir-185-5p
;
hsa-mir-6738-5p
;
hsa-mir-5194
;
hsa-mir-1914-3p
;
hsa-mir-423-5p
;
hsa-mir-3184-5p
;
hsa-mir-3123
;
hsa-mir-6858-5p
;
hsa-mir-4689
;
hsa-mir-1255b-5p
;
hsa-mir-1255a
;
hsa-mir-766-5p
;
hsa-mir-3605-5p
;
hsa-mir-4784
;
hsa-mir-3150b-3p
;
hsa-mir-3928-3p
;
hsa-mir-4330
;
hsa-mir-4709-5p
;
hsa-mir-212-3p
;
hsa-mir-132-3p
;
hsa-mir-5688
;
hsa-mir-495-3p
;
hsa-mir-483-3p
;
hsa-mir-1228-3p
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-8485
;
hsa-mir-5581-3p
;
hsa-mir-8064
;
hsa-mir-6872-3p
;
hsa-mir-7151-5p
;
hsa-mir-193b-3p
;
hsa-mir-193a-3p
;
hsa-mir-195-5p
;
hsa-mir-15b-5p
;
hsa-mir-16-5p
;
hsa-mir-15a-5p
Nearest miRNA
hsa-mir-1236/Upstream/445440; hsa-mir-10398/Downstream/784332;
Nearest TSS
ENST00000381078/Upstream/14220;
ENST00000606971/Downstream/10141;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/141687
,
chr6-CpG: 55/Downstream/10119
Upstream sequence
ggacctcagcacattagaaacatttgtgaatcataggacattgtcaagaaagtgaaaagacagcctacagaatgggagaaaacagtgcaatttatatacc
Downstream sequence
caataaggatttcatatccagaatatataaagacttcttacaggccaggtgtggtggctcacacctgtaatcccagcactttgggaggctgaggtgggcg
Target sequence
gaatgggagaaaacagtgcaatttatatacc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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