Basic Information
VIS ID
TVIS30016407
Fusion event
HIV-FKBP5 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.31
Reference genome
End
35567311/35599679 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1236/Upstream/129100; hsa-mir-10398/Downstream/65038;
Upstream sequence
TAATACCATCTTGATGTGTTCCCCTTGCAGACACAGAATGGGGTCTAAGAAACTTGGGCCAAACTAGAAAGGGCCTAACTCTTGAGTCAGCTCCTCCAAA
Downstream sequence
CAAGGGCTAGAGTTGGAGTGGCTTGGTAGAGCTCGCATATGGCATTTTAGTTTATGTCCCACACTCATAAATGCTGATAATTCCTTCTGTTAGACTTACT
Target sequence
gctgccgaagtgagtacTCACTACTCTTTTTTAACTCACCAGTATTAATACCATCTTGATGTGTTCCCCTTGCAGACACAGAATGGGGTCTAAGAAACTTGGGCCAAACTAGAAAGGGCCTAACTCTTGAGTCAGCTCCTCCAAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate