VISDB Viral Integration Site DataBase

VIS ID

TVIS30016411

Fusion event

HIV-SRSF3 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr6

Cytoband

p21.31

Reference genome

Start

End

36564205/36596659 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-361-5p ; hsa-mir-186-5p ; hsa-mir-124-3p ; hsa-mir-374a-3p ; hsa-mir-622 ; hsa-mir-877-5p ; hsa-mir-6866-5p ; hsa-mir-1303 ; hsa-mir-4795-3p ; hsa-mir-6721-5p ; hsa-mir-657 ; hsa-mir-7157-3p ; hsa-mir-6737-3p ; hsa-mir-5008-3p ; hsa-mir-6860 ; hsa-mir-6889-3p ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-5094 ; hsa-mir-5583-5p ; hsa-mir-3129-3p

Nearest miRNA

hsa-mir-1236/Upstream/931870; hsa-mir-10398/Downstream/25777;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/2024, chr6-CpG: 42/Downstream/64150

Nearest cancer related gene

SRSF3(OG, No orient, 0)

Upstream sequence

ATGGGGCGGGGTGGCGGGGGGGGGGAAATGGGTGCTTAGCAGTAACATTTCTTGTTTGGTTTCTAGCATTTTTGTAATTTTTTTTTCTTTACGTGCTACC

Downstream sequence

TTAAACTCTCTTGTCCTCTCTAATGGAGTTCTTTCTAAGGATCTGTGGTTTTAACTGTAGATGTTTAGATGAATGAATATTTTTGGTATTTTTCATTACA

Target sequence

aataacaggttaagtctcttaactcacggcccagatggtggtaaatgctcCTCCAGTTGTTCTCAACGTTCCAAGGAAGCTGTTTTTTTCTTCACTAATTGCTGGCTTCCTGAGGGTTAGGAGTAAAGATAATGGGGCGGGGTGGCGGGGGGGGGGAAATGGGTGCTTAGCAGTAACATTTCTTGTTTGGTTTCTAGCATTTTTGTAATTTTTTTTTCTTTACGTGCTACC