VISDB Viral Integration Site DataBase

VIS ID

TVIS30016421

Fusion event

HIV-CCND3 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr6

Cytoband

p21.1

Reference genome

Start

End

41961039/41993034 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-424-5p ; hsa-mir-16-5p ; hsa-mir-34a-5p ; hsa-mir-195-5p ; hsa-mir-138-5p ; hsa-mir-615-3p ; hsa-mir-324-5p ; hsa-mir-27b-3p ; hsa-let-7b-5p ; hsa-mir-503-5p ; hsa-mir-28-5p ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-497-5p ; hsa-mir-218-5p ; hsa-mir-7106-5p ; hsa-mir-6722-3p ; hsa-mir-765 ; hsa-mir-6836-5p ; hsa-mir-1909-3p ; hsa-mir-6132 ; hsa-mir-6754-5p ; hsa-mir-4441 ; hsa-mir-4270 ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-15b-5p ; hsa-mir-15b-3p

Nearest miRNA

hsa-mir-10398/Upstream/259424; hsa-mir-10524/Downstream/1441508;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/51061, chr6-CpG: 48/Downstream/55471

Nearby gene

CCND3(No orient, 51220)

Upstream sequence

gtctcactctttcatccaggctggagtgcagttgtacaatcatagctctctgtagccttgaactcctgggctcaggcaatcctcacacctaagcccctaa

Downstream sequence

cctcacagcatagatgatacctcattgtggttttacttggatttccctgatgattagtgatgttgaacattttcccatatatCAATATATTTGTTAAGCT

Target sequence

gtaacaagactataggcacactatatcatgcctggcttaaaaatgttttgtagagacagggtcttgatgtgttgcttaaaatggtcttgaactcctggctccaagtgatctccccaccttggcctcccaaagctctgggattacaggtggaaaccaccatacctggtctgatttacagttttttgaggaaactccataatgtttgctatagtggctgcaatagtttatattcccaccaaccgtctatgagatccc