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TVIS30016422
Basic Information
VIS ID
TVIS30016422
Fusion event
HIV-chr6 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
42756261/42788523 (Hg38)
End
42756102/42788523 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
BICRAL
;
LOC401261
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-192-5p
;
hsa-mir-4526
;
hsa-mir-4504
;
hsa-mir-6721-5p
;
hsa-mir-5191
;
hsa-mir-6836-5p
;
hsa-mir-6132
;
hsa-mir-7854-3p
;
hsa-mir-135a-3p
;
hsa-mir-7843-5p
;
hsa-mir-6879-5p
;
hsa-mir-6735-5p
;
hsa-mir-4632-5p
;
hsa-mir-4436b-3p
;
hsa-mir-9500
;
hsa-mir-6750-5p
;
hsa-mir-6822-5p
;
hsa-mir-5584-5p
;
hsa-mir-6856-5p
;
hsa-mir-6758-5p
;
hsa-mir-4311
;
hsa-mir-200a-3p
;
hsa-mir-141-3p
Nearest miRNA
hsa-mir-10398/Upstream/1054913; hsa-mir-10524/Downstream/646019;
Nearest TSS
ENST00000381078/Upstream/6496;
ENST00000394168/Downstream/32533;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/4829
,
chr6-CpG: 64/Downstream/101908
Upstream sequence
gttagccaggctggtctcgaactcctgacctcaggtgatccacgcacctaggcctcccaaaatgttgggattataggtgtgagccaccatgcctggccgg
Downstream sequence
gagcagcattcttaaggaattcaagacacaggaagaacacttgcctttagtgggagcaagacaacgcagtgtggcagaagacaaagaatgggggcacaag
Target sequence
caggtatgcaccaccacacccagctaattttgtatttttagtagagacgggtccaccatgttagccaggctggtctcgaactcctgacctcaggtgatccacgcacctaggcctcccaaaatgttgggattataggtgtgagccaccatgcctggccgg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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