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TVIS30016426
Basic Information
VIS ID
TVIS30016426
Fusion event
HIV-ICK integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
52878088/53013290 (Hg38)
End
52877816/53013290 (Hg38)
Orient
-
Location type
Intronic
Target gene
ICK
miRNAs that regulate target gene
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-101-3p
;
hsa-mir-4760-3p
;
hsa-mir-3942-3p
;
hsa-mir-449c-3p
;
hsa-mir-27b-3p
;
hsa-mir-27a-3p
;
hsa-mir-513a-5p
;
hsa-mir-6825-5p
;
hsa-mir-7106-5p
;
hsa-mir-766-5p
;
hsa-mir-6077
;
hsa-mir-8086
;
hsa-mir-6770-5p
;
hsa-mir-3179
;
hsa-mir-4310
;
hsa-mir-7157-5p
;
hsa-mir-4756-3p
;
hsa-mir-3919
;
hsa-mir-205-3p
;
hsa-mir-3154
;
hsa-mir-943
;
hsa-mir-4439
;
hsa-mir-3136-5p
;
hsa-mir-6516-3p
;
hsa-mir-3152-3p
;
hsa-mir-205-5p
;
hsa-mir-892a
;
hsa-mir-6715b-3p
;
hsa-mir-6715a-3p
;
hsa-mir-548c-3p
Nearest miRNA
hsa-mir-10398/Upstream/864249; hsa-mir-10524/Downstream/263703;
Nearest TSS
ENST00000381078/Upstream/17912;
ENST00000461222/Downstream/38701;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/18321
,
chr6-CpG: 67/Downstream/48190
Upstream sequence
attactgacctttacagagttgtaactaggtgccaggtattattctaaattcttttcaagtattaactcattagtcctcaaagcaattgtatcaggtaag
Downstream sequence
tactattattatccttattttacagatgaggaaaatgaggagcagagaagccagataacttgcataggtatcaagctactaaacagcagagctgagattt
Target sequence
AGTAATGTGGataacaatctacaaatattaacacagcgctttatgcttttcaaaatatcttaaaaacatcatggcctttgatcctcatgaacaaccctgtctggtaggtaagacatgcactataatcttcctttgataaatgaggaaactgaatccatagggattaataacaattactgacctttacagagttgtaactaggtgccaggtattattctaaattcttttcaagtattaactcattagtcctcaaag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT4
Sample type
PBMC
Age
39
Gender
Male
CpG Island Information
×
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