Basic Information
VIS ID
TVIS30016427
Fusion event
HIV-PRIM2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
57289869/57425071 (Hg38)
End
57289756/57425071 (Hg38)
Orient
-
Location type
Intronic
Target gene
PRIM2
miRNAs that regulate target gene
hsa-mir-665 ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-4266 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6894-5p ; hsa-mir-7160-5p ; hsa-mir-202-3p ; hsa-mir-98-5p ; hsa-mir-4500 ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-7162-3p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-4779 ; hsa-mir-4695-5p ; hsa-mir-890
Nearest miRNA
hsa-mir-10398/Upstream/34859; hsa-mir-10524/Downstream/13951889;
Nearest TSS
ENST00000381078/Upstream/45124; ENST00000421261/Downstream/68784;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/202558, chr6-CpG: 35/Downstream/428805
Upstream sequence
TAGGATAGAGGAATACCaaatgaatgaataaatgaataaataaaCATGTATACACATATATTTTATCTTGGTTAAATAGATAACTGTGAAATATTATACT
Downstream sequence
TAGGAATAGCTTTGACTTTTCAAGTTTTTCTCACTTAAAATATGTTCTGTGTCTATCTAGTTTTTATTATGCAGCGTGTATTTAAATTATATTTTCATTT
Target sequence
GTTCCCTTAAGTGTAGGATAGAGGAATACCaaatgaatgaataaatgaataaataaaCATGTATACACATATATTTTATCTTGGTTAAATAGATAACTGTGAAATATTATACT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate