Basic Information
VIS ID
TVIS30016428
Fusion event
HIV-ADGRB3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q12
Reference genome
GRCh37/hg19
Start
69785326/69075434 (Hg38)
End
69785394/69075434 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADGRB3
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10398/Upstream/11685222; hsa-mir-10524/Downstream/2301526;
Nearest TSS
ENST00000381078/Upstream/436758; ENST00000604969/Downstream/156972;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/440280, chr6-CpG: 53/Downstream/720966
Upstream sequence
AGCACATTGAATAATGCAGTGTGAAAAATCCATGGTGTTATCTTGAAGGTCACGGCAGGTACTCAATTCATAATTATTGAAGTAAATTTAAAATCTAGCA
Downstream sequence
AGTTGACAAACTCCAGAAATGAACATCTCTTATCTCTAGGAAACATCAACTAGAGGCTGAAGAGGAGGTAGTGGTGGTGATTATACATGTGCATAATATA
Target sequence
TTTTCACTTAAAATTTCATTAGACATTATCCTATACAACCATGATATGCTAATTAAGAGGATATTGCA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate