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TVIS30016429
Basic Information
VIS ID
TVIS30016429
Fusion event
HIV-PHIP integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
79675187/78965470 (Hg38)
End
79675403/78965470 (Hg38)
Orient
+
Location type
Intronic
Target gene
PHIP
miRNAs that regulate target gene
hsa-mir-21-5p
;
hsa-mir-16-5p
;
hsa-mir-760
;
hsa-mir-5011-5p
;
hsa-mir-218-5p
;
hsa-mir-3163
;
hsa-mir-548e-5p
;
hsa-mir-545-3p
;
hsa-mir-6083
;
hsa-mir-573
;
hsa-mir-3616-5p
;
hsa-mir-190a-3p
;
hsa-mir-4795-5p
;
hsa-mir-4729
;
hsa-mir-6074
;
hsa-mir-1277-5p
;
hsa-mir-186-5p
;
hsa-mir-3133
;
hsa-mir-664b-3p
;
hsa-mir-579-3p
;
hsa-mir-5696
;
hsa-mir-664a-3p
;
hsa-mir-3924
;
hsa-mir-105-5p
;
hsa-mir-33a-3p
;
hsa-mir-4307
;
hsa-mir-4524b-3p
;
hsa-mir-7853-5p
;
hsa-mir-129-5p
;
hsa-mir-3680-3p
;
hsa-mir-450b-5p
;
hsa-mir-4762-5p
;
hsa-mir-507
;
hsa-mir-518a-5p
;
hsa-mir-527
;
hsa-mir-548aw
;
hsa-mir-551b-5p
;
hsa-mir-557
Nearest miRNA
hsa-mir-10398/Upstream/426161; hsa-mir-1202/Downstream/11347272;
Nearest TSS
ENST00000381078/Upstream/67278;
ENST00000604516/Downstream/17473;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/54470
,
chr6-CpG: 131/Downstream/111625
Upstream sequence
ttatgttacactTTAAACACTCTGCTAAAGTTACAAAAGTGTCTCTGCCTCCCAAATGCACACTTTCTTGGGTGAATAGTAATTAATAAAACAATTTCAT
Downstream sequence
CCTAACACACACTTACCATTATTAGGTATAAGCTCCATATCCCAAGGACTCATCTTTTCTGTATCTCCATTGTCCCAGCTTAAAGAAAGAAAAATCatta
Target sequence
GTTTTGCTGTAATAAATTAATTTCAATCaattccaagtaggcaagagttatatctatcttcttcactgctgaatctcccctacttcaaggtgtacaataataaatatttgccaaatgaatgTTTTCTATTTGATACTCACAACTGTAAGTGGTAGCATGTTAGCAAATCTTAAATAATTTCTTAAGAAATTAACTCCATAATGGAGAAACAAAAAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT5
Sample type
PBMC
Age
44
Gender
Male
CpG Island Information
×
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