Basic Information
VIS ID
TVIS30016430
Fusion event
HIV-ZNF292 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
87934079/87224361 (Hg38)
End
87934235/87224361 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZNF292
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-196a-3p ; hsa-mir-7153-5p ; hsa-mir-146b-5p ; hsa-mir-146a-5p ; hsa-mir-3925-5p ; hsa-mir-3120-3p ; hsa-mir-32-3p ; hsa-mir-1273g-3p ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-508-5p ; hsa-mir-200a-3p ; hsa-mir-141-3p ; hsa-mir-6873-3p ; hsa-mir-4795-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-3675-3p ; hsa-mir-7151-5p ; hsa-mir-5003-3p
Nearest miRNA
hsa-mir-10398/Upstream/8685052; hsa-mir-1202/Downstream/3088381;
Nearest TSS
ENST00000381078/Upstream/10623; ENST00000466062/Downstream/9163;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/68302, chr6-CpG: 30/Downstream/98078
Nearest cancer related gene
ZNF292(TSG, No orient, 0)
Upstream sequence
taatatagttattttgttgtattctgtattccatcttgggcttcctgaacctcctaaataacttttttttcaatttgcataccttaagattccctctttt
Downstream sequence
atctatctgccatctctatagttttgcctttttcagaatgtcacgtaattaaagcttttcattcaagcttctttcacatagcattgtatatttaacattc
Target sequence
gtgttgtatagttttatagattttgacaaatgaaaatagtgtcgtgtgtccaccattacagtagtatacatagtagtttcactccctaaaaaaaaaaacaacaaaaaaactgtgtttcatctatccagccttctcccaaacacctgacaactactt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate