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TVIS30016442
Basic Information
VIS ID
TVIS30016442
Fusion event
HIV-BACH2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q15
Reference genome
GRCh37/hg19
Start
90745668/90035949 (Hg38)
End
90745493/90035949 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA6G
Target gene
BACH2
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-29c-3p
;
hsa-mir-615-3p
;
hsa-mir-8064
;
hsa-mir-1277-5p
;
hsa-mir-190a-3p
;
hsa-mir-6083
;
hsa-mir-5011-5p
;
hsa-mir-656-3p
;
hsa-mir-410-3p
;
hsa-mir-3942-3p
;
hsa-mir-1324
;
hsa-mir-8485
;
hsa-mir-6797-3p
;
hsa-mir-6076
;
hsa-mir-6807-3p
;
hsa-mir-217
;
hsa-mir-509-5p
;
hsa-mir-509-3-5p
;
hsa-mir-4418
;
hsa-mir-6749-3p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-2355-5p
;
hsa-mir-15b-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-6832-3p
;
hsa-mir-620
;
hsa-mir-1270
;
hsa-mir-4531
;
hsa-mir-5703
;
hsa-mir-4516
;
hsa-mir-4434
;
hsa-mir-5695
;
hsa-mir-3145-5p
;
hsa-let-7g-3p
;
hsa-let-7a-2-3p
;
hsa-mir-374b-5p
;
hsa-mir-374a-5p
;
hsa-mir-4791
;
hsa-mir-3201
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-369-3p
;
hsa-mir-5583-3p
;
hsa-mir-4517
;
hsa-mir-557
;
hsa-mir-507
;
hsa-mir-4726-3p
;
hsa-mir-6764-5p
;
hsa-mir-1915-3p
;
hsa-mir-6840-3p
;
hsa-mir-142-5p
Nearest miRNA
hsa-mir-10398/Upstream/11496640; hsa-mir-1202/Downstream/276793;
Nearest TSS
ENST00000381078/Upstream/27122;
ENST00000569865/Downstream/182296;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/148015
,
chr6-CpG: 227/Downstream/259127
Upstream sequence
caataacagaagaaaaactcaagcatgtctgaatcccagGTTTCCACTATATTTTATTAAAGAAAATACCCAAGGAGAAGGGGCATGATGAGCAGCATAT
Downstream sequence
GGAGACAATTTTTGTTCTAAAATTAAGCCCATTTACTTACATTTCATTTCTACGAAGGGGTTATGTGTAAGATTGGGGGTGGGTAGAGGAAGAACCATTC
Target sequence
ctcttttaaaaattatagacgtttaggctcaaagatattaaacaatttactcaaggtcgcagaaccatttagtaacaataacagaagaaaaactcaagcatgtctgaatcccagGTTTCCACTATATTTTATTAAAGAAAATACCCAAGGAGAAGGGGCATGATGAGCAGCATAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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