Basic Information
VIS ID
TVIS30016444
Fusion event
HIV-BACH2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q15
Reference genome
End
90745800/90035944 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10398/Upstream/11496635; hsa-mir-1202/Downstream/276798;
Upstream sequence
agtaacaataacagaagaaaaactcaagcatgtctgaatcccagGTTTCCACTATATTTTATTAAAGAAAATACCCAAGGAGAAGGGGCATGATGAGCAG
Downstream sequence
GTATTTCCTTAAGTGAAAATAAAATGGGTTTCCTTTGAGTCACAAAAATAATTCTAAAACAGGGCATTGCTTCTCATCAGCTTTTTTTTTCTGGGCTACA
Target sequence
CATATGGAGACAATTTTTGTTCTAAAATTAAGCCCATTTACTTACATTTCATTTCTACGAAGGGGTTATGTGTAAGATTGGGGGTGGGTAGAGGAAGAACCATTCTAAGAGAACACCATAGAACTGTAGCTCTTCAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate