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VISDB
Viral Integration Site DataBase
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TVIS30016450
Proximate region of VIS (GRCh38)
VIS
Enhancer
Enhancer/Promoter
Promoter
Gene
89855578
89926529
90296908
90033150
90038748
90060522
90065273
90047221
90050834
90028300
90030590
90044343
90046218
90039325
90041111
90025225
90026471
90072701
90073069
90076243
Basic Information
VIS ID
TVIS30016450
Fusion event
HIV-BACH2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q15
Reference genome
GRCh37/hg19
Start
90785962/90076243 (Hg38)
End
90786038/90076243 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6G
Target gene
BACH2
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-29c-3p
;
hsa-mir-615-3p
;
hsa-mir-8064
;
hsa-mir-1277-5p
;
hsa-mir-190a-3p
;
hsa-mir-6083
;
hsa-mir-5011-5p
;
hsa-mir-656-3p
;
hsa-mir-410-3p
;
hsa-mir-3942-3p
;
hsa-mir-1324
;
hsa-mir-8485
;
hsa-mir-6797-3p
;
hsa-mir-6076
;
hsa-mir-6807-3p
;
hsa-mir-217
;
hsa-mir-509-5p
;
hsa-mir-509-3-5p
;
hsa-mir-4418
;
hsa-mir-6749-3p
;
hsa-mir-211-5p
;
hsa-mir-204-5p
;
hsa-mir-2355-5p
;
hsa-mir-15b-3p
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-6832-3p
;
hsa-mir-620
;
hsa-mir-1270
;
hsa-mir-4531
;
hsa-mir-5703
;
hsa-mir-4516
;
hsa-mir-4434
;
hsa-mir-5695
;
hsa-mir-3145-5p
;
hsa-let-7g-3p
;
hsa-let-7a-2-3p
;
hsa-mir-374b-5p
;
hsa-mir-374a-5p
;
hsa-mir-4791
;
hsa-mir-3201
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-369-3p
;
hsa-mir-5583-3p
;
hsa-mir-4517
;
hsa-mir-557
;
hsa-mir-507
;
hsa-mir-4726-3p
;
hsa-mir-6764-5p
;
hsa-mir-1915-3p
;
hsa-mir-6840-3p
;
hsa-mir-142-5p
Nearest miRNA
hsa-mir-10398/Upstream/11536934; hsa-mir-1202/Downstream/236499;
Nearest TSS
ENST00000381078/Upstream/67416;
ENST00000569865/Downstream/142002;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/188309
,
chr6-CpG: 227/Downstream/218833
Upstream sequence
TACAATCTGTTTCCCTTAGGGATGGAAGGTGATGAGGGGAGACCAGTGATAGGTGAGATTTAAAGACACGTAAAGGAAGGGTGGAAAAGAAATGCATTAT
Downstream sequence
CTTTTACTGAACACCTAATATCACCCAGCTGTGAATAAAAGAAAAAGAATCTCACTCTGACCAATTCATACAAATTGACTAATACTTATTCCCTTATGGT
Target sequence
GTTACCGAGCGAATGAGGATTAAATCTTCATAATGCATGTCAGATTCTCACAAAAAGAAAATAAAACAAGGGCAAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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