Basic Information
VIS ID
TVIS30016460
Fusion event
HIV-chr6 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q21
Reference genome
GRCh37/hg19
Start
110261318/109940115 (Hg38)
End
110261406/109940115 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA6F
Nearest miRNA
hsa-mir-10398/Upstream/3155895; hsa-mir-1202/Downstream/9128932;
Nearest TSS
ENST00000381078/Upstream/113593; ENST00000275169/Downstream/38141;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/248549, chr6-CpG: 143/Downstream/38047
Nearby gene
GPR6(No orient, 38979)
Upstream sequence
actgcctctggctggaagtgacatacatcacttccactcacatttccctggccagaacttcactatggccctaccctactcaaaggaggtaggaagtgta
Downstream sequence
CCCTAGCATACCCTGCCATGCCATGCCTGTGTCTTGCACGCGCTGCTCCAACTCTCTAGAACACCTCTCTCCTCCCCTTTCCCATCTATCCCAGTCTTTC
Target sequence
gtctcttgtgtggtcaggaaagaaagaaCCAGATGTTACTGATGTTGGGGCCCCTGGTGCTCTAAGCATGCTGAAAACCTTGTGCTCT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate