Basic Information
VIS ID
TVIS30016467
Fusion event
HIV-EPB41L2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
131375756/131054616 (Hg38)
End
131375736/131054616 (Hg38)
Orient
-
Location type
Intronic
Target gene
EPB41L2
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-34a-5p ; hsa-mir-1229-3p ; hsa-mir-331-3p ; hsa-mir-222-3p ; hsa-mir-10a-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-10398/Upstream/4569903; hsa-mir-1202/Downstream/737556;
Nearest TSS
ENST00000381078/Upstream/38774; ENST00000479599/Downstream/7960;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/688025, chr6-CpG: 144/Downstream/7675
Nearby gene
AKAP7(No orient, 81069)
Upstream sequence
TTATCCCTACTTATCTCTATGTGTCCCTGTAGGCCTCCtcaggtcccttcaggtctcttcaggtctctGTTTGTCACTGATAGTCCCTGTTCGGGCGCCA
Downstream sequence
CTtgtggcacattgccacagttactacttgagaccttcactacaacagttactactgttactacttgagaccgtcattacgagactgaaggaagggacaa
Target sequence
TAGTCCCTGTTCGGGCGCCA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate