Basic Information
VIS ID
TVIS30016472
Fusion event
HIV-chr6 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
149407304/149086168 (Hg38)
End
149407428/149086168 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/8402285; hsa-mir-1202/Downstream/2016507;
Nearest TSS
ENST00000381078/Upstream/19992; ENST00000451095/Downstream/131758;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/207456, chr6-CpG: 113/Downstream/230714
Nearby gene
UST(No orient, 9178)
Upstream sequence
CAATCACTTTTTGTGTCAAGTAATATTGGTGATTTTCTGTACTCCATAATTGGGGTTATAAATATAATCCAAGTTATATTATATGACTACTTATACTTTT
Downstream sequence
AGCAAAAATGCAAGCAGGACAAGGGTGCAATCGGGCTCAAGGGCAACTGGAACCAGGGACTGAAATGCTACCTGGTGTTTCTCCCTCTCTCTCCCACCCT
Target sequence
GTTAATTGTATGTACTTGTTGGTTTCGGGTGCCAGAAATAATCCAACTCTAACAAGTTCAGACAAAAAGAAAATCTACTGGAAGAGCAGAAGGGTATCTATAAAATCAGAAAAAGAATTGAAAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate