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TVIS30016473
Basic Information
VIS ID
TVIS30016473
Fusion event
HIV-PPIL4 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
149847786/149526650 (Hg38)
End
149847920/149526650 (Hg38)
Orient
+
Location type
Intronic
Target gene
PPIL4
miRNAs that regulate target gene
hsa-mir-877-5p
;
hsa-mir-320a
;
hsa-let-7a-3p
;
hsa-let-7b-3p
;
hsa-let-7f-1-3p
;
hsa-mir-98-3p
;
hsa-mir-3591-5p
;
hsa-mir-142-3p
;
hsa-mir-524-5p
;
hsa-mir-520d-5p
;
hsa-mir-95-5p
;
hsa-mir-4666a-3p
;
hsa-mir-3163
;
hsa-mir-4280
;
hsa-mir-548l
;
hsa-mir-4282
;
hsa-mir-548n
;
hsa-mir-300
;
hsa-mir-381-3p
;
hsa-mir-489-3p
;
hsa-mir-3148
;
hsa-mir-3913-3p
;
hsa-mir-3662
;
hsa-mir-548e-5p
;
hsa-mir-891a-5p
;
hsa-mir-508-5p
;
hsa-mir-7703
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-566
;
hsa-mir-6789-3p
;
hsa-mir-650
;
hsa-mir-3612
;
hsa-mir-661
;
hsa-mir-4252
;
hsa-mir-6499-3p
;
hsa-mir-2467-3p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-1827
;
hsa-mir-4487
;
hsa-mir-558
;
hsa-mir-3160-3p
;
hsa-mir-1273f
;
hsa-mir-4708-5p
;
hsa-mir-6088
;
hsa-mir-4770
;
hsa-mir-143-3p
;
hsa-mir-6860
;
hsa-mir-612
;
hsa-mir-5189-5p
;
hsa-mir-3187-5p
;
hsa-mir-1285-3p
;
hsa-mir-17-3p
;
hsa-mir-4793-3p
;
hsa-mir-766-3p
;
hsa-mir-939-3p
;
hsa-mir-6840-3p
;
hsa-mir-6849-3p
;
hsa-mir-1273g-3p
;
hsa-mir-4459
;
hsa-mir-652-3p
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-4695-5p
;
hsa-mir-1227-3p
;
hsa-mir-1247-3p
;
hsa-mir-1262
;
hsa-mir-4327
;
hsa-mir-455-3p
;
hsa-mir-4649-3p
;
hsa-mir-4701-3p
;
hsa-mir-4722-5p
;
hsa-mir-4768-3p
;
hsa-mir-542-3p
;
hsa-mir-6516-5p
;
hsa-mir-6736-5p
;
hsa-mir-6742-3p
;
hsa-mir-6776-5p
;
hsa-mir-6807-5p
;
hsa-mir-6808-5p
;
hsa-mir-6893-5p
;
hsa-mir-940
Nearest miRNA
hsa-mir-10398/Upstream/8842767; hsa-mir-1202/Downstream/1576025;
Nearest TSS
ENST00000381078/Upstream/8786;
ENST00000446392/Downstream/19388;
Nearest CpG islands
None/Target,
chr6-CpG: 120/Upstream/69597
,
chr6-CpG: 64/Downstream/19245
Upstream sequence
ATTCGCCTAGAATTCACAGAATCATCAAAATATGTCATTAGAAAACCACCAACTGATACCTAGTTTTTCTAAATATCTCTTTCACTAATTCTAAGGATTA
Downstream sequence
CAAACAAACAAAAACATAAATCAATTCCTATTTAGTTTCCATTCTAAATCCTATCCAATCCCACAATGCTGATTTCCTTAAAACATCTAAATTTATGTTA
Target sequence
CCTTCTTATTGGCCCAAATCTAGAGAATATTATTTCCAGATCCTCATCTGTGGTCACTGGGTTCAATTTACACACAAACAGTACATTTTCTGGAGGTTTAATATCTGCATCAGGTAGGTCTCCCACCTAAATTA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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